The phrase "associate to and dissociate" is not correct in standard written English.
It may be intended to describe the process of forming connections and then breaking them, but the phrasing is awkward and unclear.
Example: "In psychology, individuals may associate to and dissociate from certain memories during therapy."
Alternatives: "connect and disconnect" or "link and unlink".
Conformational diversity may allow Nup98 and Nup116p to bind to multiple targets within the NPC or to associate and dissociate quickly from the NPC to increase the mobility of the nucleoporins, as described for Nup98, which shuttles in a transcription-dependent manner (Griffis et al. 2002, 2004).
The ability of GPCR dimers and oligomers to associate and dissociate rapidly suggests relatively small standard free energy differences between dimeric and monomeric GPCRs compared to those of protein complexes stabilized by multiple specific bonds.
The ability of atoms to associate and dissociate is responsible for most of the physical changes observed in nature, and is the subject of the discipline of chemistry.
Similarly, in type II (dissociated) fatty acid synthases and in many other enzymes that react with ACP-bound groups, the ACP must be able to associate and dissociate with a variety of protein partners and must be capable of exposing the fatty acyl chain to thioesterases and other enzymes.
CaM acts as both a dedicated regulatory subunit and a promiscuous binding partner depending on the specific target (Saucerman and Bers, 2012), and whereas promiscuous CaM is free to associate with and dissociate from target proteins as a function of Ca2+, dedicated CaM remains bound irrespective of changes in the Ca2+ concentration.
This is plausible, because while the DNA affinity of DBD-A DBD-B (~50 nM K DBD-A DBD-Bantially higher than its DBD-A DBD-Bty, those of the individual DBD-A (2 μM K d) and DBD-B (20 μM K d) are not, and as with the intact Rpa heterotrimer, they are thought to associate with and dissociate from DNA sequentially (Arunkumar et al., 2005; Fan and Pavletich, 2012; Fanning et al., 2006).
It is increasingly appreciated that the rates at which drugs associate with and dissociate from receptors — the binding kinetics — directly impact drug efficacy and safety.
It was demonstrated that nucleolar proteins rapidly associate with and dissociate from nucleolar components in continuous exchanges with the nucleoplasm (Phair and Misteli 2000).
Earlier it has been shown that CSP 310-like native proteins are present in cytoplasm [ 18] and mitochondria [ 19] of cereals with different cold tolerance, and that CSP 310 could associate with and dissociate from mitochondria [ 20].
As for the nucleolus, it was demonstrated that nucleolar proteins rapidly associate with and dissociate from nucleolar components in a continuous exchange with the nucleoplasm (Chen and Huang 2001; Dundr et al. 2004; Phair and Misteli 2000; Snaar et al. 2000).
