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As a further control, we also directly applied HUMAnN2 to its underlying pangenome database to associate pathways with >4,000 microbial species.
The possible functional categories that govern the responses of CAMTA1 dependent positively regulated genes of leaf and root tissue featured several regulators and associate pathways.
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Recent Genome Wide (GWAS) and Candidate Gene Case-Control Association Studies have also indicated an association of Telomere and associated pathways related genes with T2 DM.
Here, we propose the possible mechanisms, in the light of existing knowledge, to understand the association of T2 DM with telomeres and associated pathways.
In the case of pathway enrichment analysis, biological pathways with high enrichment ratios and low p-values can be thought of as candidates for the associated pathways.
Identification of these modifier genes and the associated pathways may lead to novel therapeutic strategies.
I know that in my gene example before, there are a group of genes that are actually associated pathways.
When "daikenchuto" was entered as a query in KampoDB, the "Functional analysis" component predicted "serotonergic synapse" and "arachidonic acid metabolism" as the associated pathways.
MicroRNAs (miRs) are non-coding RNAs that act as post-transcriptional regulators of multiple proteins and associated pathways.
Mirzaei M, Gupta VB, Chick JM, Greco TM, Wu Y, Chitranshi N, et al. Age-related neurodegenerative disease associated pathways identified in retinal and vitreous proteome from human glaucoma eyes.
Interestingly, the PI3K-AKT-activation pathway (35 genes from the reactome gene-set) was recently shown to be among the most strongly associated pathways for ICV in an enrichment analysis testing 671 Reactome gene-sets using the same cohorts42.
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