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We also wish to thank Alexia Massa-Gallucci, Ilaria Coscia, John Coyne and Maria Sala-Bozano for their assistance sample collection and genetic analysis, and Alan McDevitt for his thorough and constructive inputs on the manuscript.

This work was funded by an American Philosophical Society grant to MR. We thank the American Museum of Natural History for granting access to their collections and P. Sweet for his assistance sampling the specimens.

The authors would like to thank the staff of the laboratories of the University of Pittsburgh Medical Center for their assistance with sample acquisition, and Steve Wisniewski for initial sample size calculations.

We are thankful to all patients participated in this study, Victor Castro at MGH for assistance in sample collection, Christine Suver and the Rosetta Gene Expression Laboratory for sample preparation.

We thank Man-Yin Tin for assistance with sample processing in the laboratory, and the staff at OIST's sequencing center for sequencing the samples.

We thank M. Ruminy for assistance with sample preparation.

We thank J. López-Ramos and R. McGrath for assistance with sample collection, preparation, and analyses.

D. M. W., J. B. H. and F. W. L. provided assistance with sample synthesis.

We are grateful to S. Sikorski for assistance in sample preparation.

Hubisz, M. J. et al. Inferring weak population structure with the assistance of sample group information.

We thank C. Zwimpfer and B. Ross for assistance with sample processing and electron microscopy.