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The ENCODE Project Consortium assigns function to 80.4% of the genome (ENCODE Project Consortium 2012).
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A classical and still vigorous branch of neuroscience, best referred to as 'functional neuroanatomy', assigns functions to specific areas in the brain.
Using these signatures, we generated a catalog of 297 functional modules, and we assigned function to 144 previously uncharacterized genes, including mRNA splicing and DNA damage checkpoint factors.
This has resulted in substantial research efforts in assigning function to all identified open reading frames – referred to as functional genomics.
In the postgenomic era, the ability to quickly, efficiently, and inexpensively assign function to the zebrafish proteome is critical.
Within this new reality lies the challenge of developing large-scale approaches to assign function to the new genes and place them in pathways.
The function of most CNCs remains elusive although recent studies have begun to assign function to a fraction of them.
Beyond evolutionary biology, understanding of domain evolution has a role in assigning function to a rapidly increasing body of data associated with proteomics.
Mapman was used to assign function to the Actinidia NRs and thus to their constitutive ESTs.
However, looking to other studies helped to assign function to some of our candidates.
Reverse genetic approaches are often used to assign function to Plasmodium-specific genes.
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