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The random numbers for group assignment were generated by the research assistant (not the counselors) of the project using a personal computer before subject recruitment.
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The assignment was generated using a random number generator in Excel, with a 2 to 1 probability of assignment to the intervention vs. the waitlist.
When complete twin pairs were always assigned to the same treatment or opposite treatments, a treatment assignment was generated for a single twin in the pair, automatically determining the second twin's assignment.
After eligibility checklist (including safety laboratories) was completed, randomized treatment assignment was generated by central computer using permuted blocks within strata.
Random assignment was generated by using computer software.
The random code for group assignment was generated by computer.
Random doe breeding assignments resulting in sire-daughter, dam-son, or full sibling matings were nullified and a new doe breeding assignment was generated.
Because multiple GO functions were assigned to a single unigene in some cases, 76,975 assignments were generated from the 66,582 unigenes.
Assignments were generated in blocks that randomly varied in size between 2 and 8.
Randomization assignments were generated in blocks of four and stratified according to trial center.
Randomisation assignments were generated and maintained separately in a sealed, opaque, sequentially numbered envelope [ 12].
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