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The run-time for the taxonomic metagenome assignment was measured as the time to find homologs and to assign taxon IDs to all sequences.
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To evaluate the cluster purity, each cluster is assigned to the class which is most frequent in the cluster, and then the accuracy of this assignment is measured by counting the number of correctly assigned samples and dividing by n the number of data in the cluster.
Empiric assignment accuracy was measured as the average probability pk* with which each isolate was assigned to the correct host source k*.
With regards to the measured indices, OS was measured from assignment to the date of death from any cause; FFS indicated the first failure at any site; and LRFS and DMFS were recorded as the first local or remote failure, respectively.
TTP was measured from random assignment to date of documented progression with censoring at date of last visit or at date of death.
Overall survival (OS) was measured from date of assignment until death of any cause.
Progression-free survival (PFS) was measured from the date of assignment until disease progression or death of any cause.
Time to progression (TTP) was measured from the date of random assignment until disease progression.
Overall survival (OS) was measured from the date of random assignment until death of any cause.
Survival was measured from the date of random assignment to either the date of death or the last follow-up.
PFS was measured from the day of the random assignment to the first evidence of progression or death.
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CEO of Professional Science Editing for Scientists @ prosciediting.com