Our analysis of the repertoire of M. tuberculosis proteins, using a multitude of sensitive techniques, has generated a resource of information including structural and functional domain assignments, potential drug-targets and small-molecule binders including FDA-approved drugs.
This assumption implies that our study observes (and controls for) all of the variables that simultaneously influence both treatment assignment and potential outcome.
Here, we present an automatic assignment of potential cognate ligands to domains of enzymes in the CATH and SCOP protein domain classifications on the basis of structural data available in the wwPDB.
Assignment of potential transmembrane segments (TMSs) was based on hydropathy, amphipathicity and similarity analyses as well as transmembrane β-strand predictions.
This root assignment allows potential dependencies between every latent variable.
To assess population assignment and potential hybrid ancestry of individuals across the hybrid zone, we delimited 13 populations along a transect running northwest to southeast from the Sierra Nevada in northeastern California into west-central Nevada.
In this assignment analysis potential sources have thus been considered in two ways: (i) North American populations could be the source of multiple introductions in CSE Europe (either primary or secondary) and (ii) European outbreaks could be the source of secondary introductions in CSE European locations where WCR had already been observed.
On Saturday, as a blinding sandstorm swept across a sprawling former Iraqi Army base near Falluja, Marine commanders were getting assignments for potential targets, studying maps and planning lines of attack for a battle that they expect could come in the next few days.
In the target-centric LeMoNe network, the potential assignment of FlhD to the flagella modules is compared to the much better scoring assignments of FliA and/or FlhC and therefore not deemed significant enough.
"Joe has a different potential assignment: He's going to be, I hope, the vice president of the United States," she said.
