9 The figure shows results for various thresholds as a cost effectiveness acceptability curve (figure) to illustrate uncertainty regarding assignment of threshold values for willingness to pay.
Regression models associated with non-leaf nodes are only used for the assignment of categorisation thresholds.
This made the assignment of gap thresholds for specific levels of phylogenetic accuracy fairly straightforward, without being necessarily concerned with other determinants of phylogenetic accuracy.
In a tree-based representation where A k × m − 1left and A n − k × m − 1right are the left and right children of A, respectively, there are two scenarios for the unsupervised assignment of the threshold γ: If exactly one child of the H2A.Z node is a leaf, the threshold is optimised to maximise the prediction accuracy of the respective model.
The assignment of the threshold will be discussed in result and discussion section.
To guide our assignment of the threshold for significant fold changes phosphorylation, we first graphed the distribution of the non-phosphorylated peptides present in the immunoprecipitated samples and determined the mean of the quantitative fold change values.
In an attempt to evade such a complication, MADE [ 56], or metabolic adjustment by differential expression, has been developed to carry out similar tasks as the previous two tools yet without the need of manual assignment of a threshold.
Applying an assignment threshold of 0.90, 91% of the MLGs (21 of 23) could be assigned to one or the other genetic cluster, confirming that the two clusters were well differentiated (FST = 0.317).
Out of the 17 different genera present in the mock community, we retrieved information for six of them, with an assignment threshold of 80%%, seven with 70%% and eight with 60%%.
A TMH shorter than 5 residues was not segmented out and remained as a part of the original TMH. Figure 3 shows an example of dynamic threshold assignment of TMHs in the protein lactose permease of Escherichia coli (PDB code: 1PV7) [26].
