Sentence examples for assignment of conserved from inspiring English sources

This confirmed the previous function assignment of conserved residues since most identified domains were still conserved among this subgroup, as were a series of residues with unknown function (further results available in Additional file 11).

These species represent two major branches in the Drosophila phylogeny and are at an evolutionary distance that allows assignment of orthology for both conserved and divergent microRNA genes.

To solve ambiguous assignments in Inparanoid clusters with more than two proteins, Bandyopadhyay et al. (2006 ) propose to use the information on protein interactions, by choosing the assignments that maximize the number of conserved interactions between two species.

Therefore, the majority of our ortholog assignments are likely accurate and incorrect ortholog assignment likely contributes little to the low extent of conserved overlaps between human and mouse.

This has implications for analyses of conserved synteny and the assignment of orthology for genes located in these regions.

The keyword and the IUPred assignment steps each individually contributed clear enrichment of conserved motifs, affirming their individual and combinatorial relevance to motif prediction (Supplementary Fig. 3).

The identification of conserved synteny is essential for the correct assignment of orthology and paralogy relationships between genes, and therefore for the evolutionary studies of gene families [ 46].

Subfamily assignment was re-evaluated on the basis of the known architecture of conserved domains.

Therefore, genome context analysis techniques [ 6] based on the identification of conserved chromosomal clusters (operons) and shared regulatory sites (regulons) are particularly efficient for accurate functional assignment of previously uncharacterized genes of sugar utilization pathways.

Comparison of the tubulysin biosynthetic gene clusters in SBCb004 and An d48 reveals a conserved architecture, allowing the assignment of cluster boundaries.

While many bad policy choices can be rethought and reformed, the development of conserved land is close to irreversible.