Genes were assigned to the functional classes according to their biochemical function using gene function databases like GO, metacyc and COG.
These unigenes were assigned to the functional categories of "metabolism", "development", "cellular process", "diverse/miscellanenous functions", "regulation overview", "response to stimulus, stress", "signaling", "transport overview", "xenoprotein, transposable element" and "unknown".
Besides 109 sequences that encoded proteins with unknown biological function or gave no hit, the sequences were assigned to the functional classes signal transduction (26), metabolism (22), transport (15), cell rescue, defense and ageing (15), protein processing (12), transcription (10), cellular biogenesis (4), energy (4), and protein synthesis (2) (Additional file 7: Figure S2).
These are assigned to the functional groups OH, C=O, C C, C O, and M O, respectively.
Among the 120 patients who completed the study, 60 were assigned to the functional treatment group, and the other 60 to the POP group.
The polygon surrounding each electrode penetration in the tessellation map characterizes the area assigned to the functional parameter at the recording site.
One of the correctly assigned variants (P299S; assigned to the severe functional disruption class; ref. 41) affected a position that we predicted to be extremely important for receptor function (see below).
We also introduce a new measure of functional modularity that only takes into account whether or not nodes that have been assigned to the same functional group connect to each other.
SiO2 POOH spectrum shows the presence of peaks at about 801 and 1053 cm−1, which are assigned to the POOH functional group [21].
The peak observed in Fig. 2(d) for GOGA nanocomposite at around 3446 cm−1 can be assigned to the O H functional groups from carboxyl or phenols.
One explanation for these differences could be the source of the data: coAP/MS approaches tend to favor stable complexes and proteins within the same complex are usually assigned to the same functional class.
