Three residues were not assigned to a model.
The average number of genes assigned to a model profile over all permutations is the expected number of genes for that model.
That leaves only seven unexplained backbone deviations, of which three were assigned to model 1 (F18, D21, and K81), and four were not assigned to a model (L133, L137, E168, and N170).
The bile binding protein shows a much larger number of residues (84 for apo and 85 for holo) to have model 1 behavior and many fewer (11, 11, 0, and 8 for apo vs 11, 9, 0, and 9 for holo) residues showing model 2 5 behavior, respectively, with three apo residues and one holo residue, respectively, not being assigned to a model.
While the model with equal rates among clades was strongly rejected in favor of variable rate models (Table 5), the highest marginal likelihood was assigned to a model with three different rates assigned to the clades I, II+III, and IV, respectively.
In comparison to other types of proteins, high-spin NP4 sym) shows somewhat more dynamics than the Src phosphopeptide-complexed homology 2 domain studied by Kay and co-workers, which is only ∼80 residues in size and consists of six β-strands and two α-helices and has 29, 10, 20, 5, and 7 model 1 5 residues, respectively, with nine residues not assigned to a model.
Patients who were diagnosed during 2009 2010 were assigned to a model-development cohort (n=304) and the others were assigned to a validation cohort (n=189).
Three hundred and three patients entered into the placebo arm of a multi-institutional sepsis study were randomly assigned to a model-building cohort (n = 200; 119 surgical) or to a predictive cohort (n = 103; 55 surgical).
In a final step, tours are generated and assigned to a network model [21].
In this scheme a score is assigned to a particular model (network structure) given some observed data.
By extension, the BioScore assigned to a candidate model f is given by (6) BioScore f = W B ∑ ı = 1 n BioScore (f ı ) n, where W B is the weight assigned to the model BioScore in the EA parameters.
