The assigned functionality of genes covers a broad range of GO categories.
Little prior knowledge exists on the function or role of virulence factor proteins FTT0482c, FTT1538c, and FTT1597; only FTT0482c has been assigned functionality as a hypothetical lipoprotein.
The other 18 (60%) contigs were assigned functionality based on BLASTP against the NR database, and all of them had homologues in either non-parasitic (C. elegans and/or C. briggsae) or parasitic nematodes.
Besides the current function annotation to CoreMitoP proteins, we exploited Arabidopsis protein interaction network to assign functionality to unknown proteins, through considering its neighbors and position in topological structures.
Basically, you assign functionality to it, so it can, say, launch your favorite app.
In an attempt to assign functionality, we performed site directed mutagenesis of each of these residues to an alanine, in addition to constructing the double mutant H115A/R138A.
Clearly, it is too early to assign functionality to these genes, except to note that many are transcribed and are presumably translated into protein products.
In the following, we shall dissect several logical, methodological, and statistical improprieties involved in assigning functionality to almost every nucleotide in the genome.
Here, we detail the many logical and methodological transgressions involved in assigning functionality to almost every nucleotide in the human genome.
However, currently, most large-scale sequencing or genotyping studies rely upon mutation prediction algorithms to assign functionality to non-synonymous variants.
