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Approximately 10 to 15% of non-small cell lung cancer patients will be assigned a stage classification according to the 7th edition of TNM that differs from that assigned by the 6th edition (the "stage shifters").
Once the neoplastic cells are located in the body, and it is determined whether they have metastasized, the cancer is assigned a stage (Table 1).
Embryos were assigned a stage based on morphological characteristics and developmental time points, such as the beginning of twitching.
2% of deceased non-responders and 61.5% of the live non-responders assigned a stage III/IV at diagnosis compared to 52.2% of the responders.
In cases where the tumor size was unknown, we assigned a stage only if the size was not a determinant in the TNM grouping.
All subjects, if applicable, were assigned a stage following in detail Braak staging recommendations and a McKeith neuropathological category following in detail recommendations by the consortium on DLB international workshop [ 4, 28].
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In rare situations where a patient is clearly known to have lost teeth due to advanced periodontal bone loss, likely to have been within the apical third of the root, then clinicians may, on a case by case basis, immediately assign a stage IV classification.
Therefore, from a practical viewpoint, it is not sufficient to simply assign a stage when making therapeutic decisions.
Reasons for this increase in staging may include physician education, introduction of less invasive staging procedures, and adoption of a collaborative staging system by SEER in 2004, which combines and standardizes information using computer algorithms to assign a stage.
In the process of assigning a stage score, the logic of the reasoning or the justification provided is considered rather than a specific set of moral beliefs or value.
Once the characteristic sequence has been determined using the EBM, the simplest way to assign a stage for a particular subject, which we adopt here, is to find the stage which is assigned the highest probability by the model, i.e. the stage, (2) that maximizes the probability of the data given the maximum likelihood event sequence.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com