Sentence examples for assigned a novel from inspiring English sources

The present study assigned a novel functional role to hnRNP A3 in age-related regulation of gene expression, opening up a new avenue for studying age-related homeostasis and underlying molecular mechanisms.

This study has successfully assigned a novel functional role to hnRNP A3 in age-related regulation of gene expression, opening up a new avenue for studying age-related homeostasis and underlying molecular mechanisms, and for developing new preventive methods and treatments for relevant age-associated diseases.

Despite several sequence and fold-independent computational methods have been proposed to detect remote binding site similarities among unrelated proteins [37], there are very few in silico studies guided by binding site comparisons that successfully predicted either the function of a protein from its 3-D structure or assigned a novel macromolecular target to an existing ligand.

If all loci are assigned for a particular readset and the combination of variants is a known ST, this ST will be returned; if a novel combination of locus variants is detected this will be assigned a novel ST.

Our results show that galectin-4 plays a unique role in the intestine and assign a novel role of this protein in controlling intestinal inflammation by a selective induction of T cell apoptosis and cell cycle restriction.

In the third part, the selected features are input to a machine learning algorithm which learns the implicit rule which separates the classes such that it will be able to correctly assign a novel example into the correct class.

While these findings assign a novel function to MHC-specific peptides in the recognition of individuality in mice, they do not preclude a role of other molecules such as the urinary volatiles [15].

In this report, we describe identification of hnRNP A3 as the mouse liver nuclear protein, which specifically bind to hFIX-AIE RNA as well as to mFIX-AIE RNA, its phosphorylation status in binding to AIE RNA, functional characterization analyzed by siRNA and age-related expression profiles of its gene and protein, thus assigning a novel functional role to this protein.

In this work we were able to assign a novel role to this already versatile protein.

From the point of view of the candidates, GBA assigns a novel target group membership (function) to a particular gene.

When assigning a novel specificity to a given MTase, the MTase gene sequence was cross-checked against other similar genes in REBASE, and the novel specificity against unassigned SMRT-derived motif data in REBASE.