For example, the application of higher HSUVs can lead to higher quality-adjusted life-year gains for more effective treatments, as each additional year free of health complications is assigned a higher quality-adjusted weight.
At the time of analysis (March 2009), our method assigned a high quality prediction for about 77.55% of the regulated genes (Supplementary table S2).
If an error nucleotide is falsely assigned a high quality score, then VarScan will retain it.
For a given (x_{0} in mathcal {I}), let (c_{x_{0}}) denote the execution path the program takes for processing x 0. Intuitively, we would assign a high-quality rating to the new input x 0 if it drives the targeted program to a previously undiscovered execution path, i.e., if (c_{x_{0}}) differs significantly from all previously explored execution paths ({c_{x} | x in mathcal {I}'}).
Statistical analyses showed that professionals from outpatient services dedicated pediatric headache assigned a higher overall quality score to the NICE CGs as compared to professionals from non-outpatient services (6.86 ± 0.38 vs 6.0 ± 0.82; p = 0.038).
For developing version 1, we assigned a higher weight to medical quality and assigned hospitals to 3 5 different performance groups according to medical quality results (i.e., based on the the German external quality assurance data and insurance claims data).
Was assigned a grade of "A" (high quality) in the following methodology domains: random-sequence generation, concealment of allocation, and selective outcome reporting; assigned a grade of "C" (unknown) in the following methodology domain: blinding.
To facilitate analysis, each curve class was combined with an efficacy cutoff and converted to a numeric curve rank such that more potent and efficacious compounds with higher quality curves were assigned a higher rank (see Supplemental Material, Table 4).
To facilitate analysis, each curve class was combined with an efficacy cutoff and converted to a numerical curve rank (Huang et al. 2009) such that more potent and efficacious compounds with higher quality curves were assigned a higher rank, and inactive (class 4) compounds were assigned a curve rank of 0. Curve ranks should be viewed as a numerical measure of compound activity.
As shown in Supplemental Material, Figure S2, each curve class was first converted to a curve rank as previously described by Huang et al. (2011), such that more potent and efficacious compounds with higher-quality curves were assigned a higher rank.
