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In particular, the SignalP program that was developed using machine learning methods [ 27], can assign signal peptide prediction scores and cleavage sites to unknown amino acid sequences with a high degree of accuracy [ 28, 29].
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Here he quickly made a significant impact on the emerging field of microwave spectroscopy, using the technique to study linear chains of carbon atoms suspected to exist in the dust clouds of interstellar space, and was able to definitively assign signals among the enormous amount of data from radio telescopes.
Use of miRNA microarray and qPCR methods requires RNA extraction and thus cannot assign signals to cell type.
1H-1H correlated spectroscopy (COSY), total correlation spectroscopy (TOCSY) and heteronuclear multiple quantum correlation spectroscopy (HMQC) was used to assign signals.
In contrast, our modeling approach identified the same two AS signals but is able to reject noisy measurements and assign signals to exons with varying degrees of splicing changes due to the modulation factor.
However, it cannot provide the spatial distribution and localization of these species within the tissues of interest, which increasingly is critical to know when assigning signal transduction functions to specific sphingolipid species.
The specific assignment of the backbone amide signals in PpcAM58 mutants was achieved using the assigned signals in the wild-type protein [ 27] as a guide.
It also assigns signaling bearers, such as bearers carrying IMS signaling and protocol packets always having higher priority over any other data bearers.
Necessary and sufficient conditions for semiglobal solvability of the nonlinear control problem are given, yielding a construction of the related feedforward feedback controller and identifying the basic information required on the measured and the assigned signals.
Only well-resolved, clearly assigned signals in the two-dimensional spectra of ghrelin and des-ghrelin were used to extract PREs (see Fig. 2).
The R1 and R1ρ relaxation rates of assigned signals that are well-resolved were determined based on the attenuations of peak intensity versus relaxation times, which follow the equation I t) = I 0) exp(− Rt), where I t) is the peak intensity at relax time t.
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