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Besides the current function annotation to CoreMitoP proteins, we exploited Arabidopsis protein interaction network to assign functionality to unknown proteins, through considering its neighbors and position in topological structures.
Basically, you assign functionality to it, so it can, say, launch your favorite app.
One potential way to better assign functionality to transcription factor binding sites, including ARORs, is to make use of chromatin analyses.
Clearly, it is too early to assign functionality to these genes, except to note that many are transcribed and are presumably translated into protein products.
However, currently, most large-scale sequencing or genotyping studies rely upon mutation prediction algorithms to assign functionality to non-synonymous variants.
To assign functionality to a regulon, we combined the results from two independent methods, automatic analysis of enrichment of GO terms and manual inspection of annotation supplemented by literature searches for each gene's annotation and function, as well as examination of the conditions under which the genes of the regulon are maximally expressed.
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In the following, we shall dissect several logical, methodological, and statistical improprieties involved in assigning functionality to almost every nucleotide in the genome.
Here, we detail the many logical and methodological transgressions involved in assigning functionality to almost every nucleotide in the human genome.
Finally, we would like to emphasize that the fact that it is sometimes difficult to identify selection should never be used as a justification to ignore selection altogether in assigning functionality to parts of the human genome.
GREAT is a tool that assigns functionality to a set of genomic regions based on nearby genes, and is thus well suited for analyses of RTSS metaclusters with an abundance of intra- and inter-genic elements.
Recently, we devised a technique known as virulence-attenuated pool (VAP) screening to help assign genetic functionality to gene products that the pathogen Vibrio cholerae requires for colonization.
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CEO of Professional Science Editing for Scientists @ prosciediting.com