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Assessments were performed using the Alda scale (Grof et al. 2002).
At implant placement and after 1, 2, 3, 4, 6, 8, 10, and 12 weeks, RFA assessments were performed using the Osstell® ISQ (Integration Diagnostics AB, Goteborg, Sweden) according to the manufacturer's instructions.
The statistical assessments were performed using the StatView software (Abacus Concepts, Inc., CA, USA).
Behavioral assessments were performed using the ADI-R [54] and the Pre-Linguistic Behavioral Pain Reactivity Scale (PL-BPRS) [56].
Behavioural assessments were performed using the Autism Diagnostic Interview Revised (ADI-R) for the children with ASD [28].
Pulmonary function assessments were performed using centralized spirometry.
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Analysis of changes between baseline and follow-up assessments was performed using Repeated Measures ANOVA for continuous variables and a chi-square test for categorical variables.
All modeling steps and calculations, including GA variable selection, model fitting, and validation as well as AD and accuracy assessment were performed using MATLAB (version 8.2, glnxa64) [121].
Image analysis and data quality assessment were performed using Genomestudio (Illumina).
For the sequences obtained from the ABI DNA analyzer, base calling and quality assessment were performed using PHRED [36] [37].
All calculations for data assessment were performed using SPSS software.
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