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Assessments of renal function derived solely from serum creatinine suffer the same shortcomings.
104 That study compared assessments of renal function in a small population of virally suppressed HIV patients to determine the most accurate method.
There is considerable interest and potential value in making available imaging methods that permit non-invasive assessments of renal function in animals.
See related research by Herrero-Morín et al., Current standard assessments of renal function for pediatric patients use serum creatinine or formulas based on serum creatinine designed for longitudinal assessment of baseline renal function.
This supports the use of linagliptin as an effective once-daily treatment option in patients with type 2 diabetes and severe RI, without the inconvenience of dose adjustments or more frequent assessments of renal function specifically for dose calculation.
As renal function-based carboplatin dosing is now used routinely in clinical practice in many multicentre protocols, it is important that accurate assessments of renal function in children are carried out consistently across paediatric oncology clinical centres.
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Because AKI biomarker levels change over time depending on the timing and severity of injury [ 9], a functional assessment of renal function might enhance biomarker performance.
Therefore, pre-therapeutic assessment of renal function is mandatory and is routinely assessed by means of laboratory tests (creatinine, glomerular filtration rate (GFR), and blood urea nitrogen (BUN)) or nuclear imaging techniques (e.g., renal scintigraphy with 99mTc-mercapto-acetylglycyl-glycyl-glycine [99mTc-MAG3]).
An assessment of renal function is required when determining the dosage of cytotoxic drugs that are renally excreted.
At baseline, patients were assessed with a physical examination (including a meticulous neurological examination), an audiogram and assessment of renal function with calculated or measured 24 h creatinine clearance, and a Cr-EDTA isotopic GFR scan.
Blood samples were collected for assessment of renal function.
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