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Therefore, the analysis was conducted excluding ratings of "not observed" such that 134 of the 822 assessments were not considered reliable for inclusion leaving 688 assessments in the analysis.
Among the independent variables with evaluations at all three assessments in the analysis, MCI and dementia (versus no cognitive impairment), a higher psychosis sub-syndrome score and affective sub-syndrome score, as well as using antipsychotic, antidepressants, anxiolytics, and anti-dementia medication were associated with lower I-ADL functioning.
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We investigated the frequency of quality assessment of randomized controlled trials within systematic reviews and the incorporation of the quality assessment in the analysis.
However, HLM analysis mitigated this loss in generalizability by using data from all patients who provided at least one assessment in the analysis.
This does limit the generalisability of our findings across all patients, but by using HLM analysis techniques and assuming the missing data were missing at random, we could include all patients who provided at least one assessment in the analysis, mitigating these concerns to a large extent.
Excessive sedation and inattention were the most common reasons for not assessing all ICDSC symptoms during the ICDSC assessments included in the analysis.
Narrowing down the time window from 7 and 14 days plus/minus 3 days as in the main analysis to plus/minus 2 days reduced number of assessments included in the analysis from 561 to 480.
Concerning the possible contamination of water due to shale gas exploitation, the results clearly showed that there is a need to further integrate risk assessment and life cycle assessment methodologies in the analysis of the environmental risk associated to shale gas development, as in Mangmeechai et al. 2013.
QSAR has provided a foundation for the physical organic chemistry and experimental medicinal chemistry and has led to ground-breaking achievements also in the environmental risk assessment and in the analysis of technological properties of industrial chemicals.
This is known as taxonomic sufficiency, a problem that has received a great deal of attention in the context of biodiversity assessment and in the analysis of environmental impacts [41] [43].
Only the attending physician assessments were used in the analysis and derivation of the model.
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