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Protocols were identified for 5/42 studies (12%); in 3 cases the assessment of selective outcome reporting changed.
First, relying on the published or final trial report may not result in accurate assessment of selective outcome reporting.
In 3/5 cases, assessment of selective outcome reporting changed, although the direction of changes was inconsistent: unclear to yes, yes to unclear, and unclear to no.
While the yield from these searches provided additional information in only 12% of studies, the additional information did result in differences in assessment of selective outcome reporting in 3 of the 5 cases.
Furthermore, trial protocols were not sought to aid the assessment of selective reporting.
The assessment of selective motor control ability for children with CP has been described by Staudt and Peacock [ 33].
Similar(46)
Several studies have sought to explain body size evolution in insular snake populations (e.g., [23], [24], [53], [54]); however, in most cases assessments of selective factors have involved only coarse data (e.g., lists of potential competitor and predator species).
It is recommended that review authors ensure that they limit the number of outcomes in the review and define them clearly as this will allow easier assessments of selective reporting, which can be done during data extraction of the included trials as long as a knowledgeable clinical person is involved.
This adjustment permits more accurate assessment of the selective pressure on DUES Ss and Ws by minimising underestimation of the importance of the less frequent ones.
We were limited to the published information and the failure to publish detail or study protocols made assessments (especially of selective outcome reporting) difficult.
For rigorous assessment of tumour cell selective targeting, we utilised isogenic normal/tumour cell line pairs that are derived from a common origin and differ only in their tumorigenic status, including the well-characterised SR5 (SR40)/SAOS-2 osteosarcoma cell pair, which has previously been used to characterise the Apoptin tNTS [ 16].
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