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The calculation of FUR allowed for the reproducible assessment of renal dysfunction following ischemic injury during long-term follow-up.
However, assessment of renal dysfunction by traditional scoring systems (i.e., AKIN criteria) is not always applicable [ 40], and some patients require haemodialysis for reasons not related to creatinine levels and urine output (e.g., hypervolemia or acidosis).
Although other factors could influence creatinine levels, and therefore this correction factor too, creatinine levels are the standard index used for assessment of renal dysfunction in acute kidney injury [ 19].
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The assessment of renal function in clinical practice occurs periodically, and the degree of renal dysfunction may change appreciably between these assessments.
Severity of renal dysfunction was assessed by the RIFLE criteria.
Similarly, semi-quantitative renal perfusion assessment seems to be associated with short-term reversibility of renal dysfunction which may theoretically help in predicting the need for renal replacement therapy and therefore optimal timing of this technique (Fig. 1) [15].
PCI is also recommended in patients with CKD amenable to revascularization after careful assessment of the risk benefit ratio in relation to the severity of renal dysfunction [ 25].
The measurement of renal dysfunction (estimated glomerular filtration rate) and waist/hip ratios in the routine assessment of patients with CHD has only recently been advocated in the UK.
They employed a 'mini-GRACE score' as many of the MINAP patients lacked creatinine values and Killip classification (substituting a history of renal dysfunction and the use of diuretics) and this approach also demonstrated good performance in an independent assessment.
The standard assessment of renal function in patients with MM includes serum creatinine and creatinine clearance, although both measurements probably underestimate the prevalence of renal dysfunction, because of the additional tubular secretion of creatinine and its dependence on extrarenal factors.
The capability of renal RI to aid in the prediction of renal dysfunction progression has been demonstrated.
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