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Approaches to seabird MPA site identification consider single- versus multiple-species approaches, mapping of marine biological "hotspots", and assessment of overlap with risks and threats.
The assessment of overlap regions was performed by dividing each IMA normalized pixel value by the average of the lower intensity regions (corresponding to one MT).
Statistical significance assessment of overlap between gene sets was performed with Fisher's exact test.
Furthermore, the blinded-for-diagnosis expert assessment of overlap muscle biopsies in comparison with PM biopsies is unique and greatly increased the strength of our findings.
The initial assessment of overlap between meta-profiles derived from the comparison of ABC-DLBCL versus COO-unclassified (CU ) DLBCL and GCB-DLBCL versus COO-unclassified (CU ) DLBCL is shown at the top of the figure, followed by the parallel analysis of gene ontology (BiNGO) and hypergeometric testing of signature enrichments.
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Briefly, it consists of digesting BAC clones with one or more restriction enzymes [ 7, 10, 12, 13] and performing pair-wise comparisons of the restriction profiles to build contigs based on the assessment of overlaps between the fingerprints [ 20].
This was achieved by: (1) evaluating two different treatment concepts that modelled differences in treatment intensity and compliance; and (2) applying broad inclusion criteria, which allowed assessment of overlapping GI conditions that frequently occur in selected patients and in the general population [ 8- 10, 20].
For general assessments of overlaps between bed-files and to extract scores for defined regions the bedTools suite (Quinlan and Hall, 2010) and UCSC tools (Kuhn et al., 2013) were used.
Quantitative assessment of the overlap between these proteoglycan associated clusters and subregions within the neostriatum agreed with our qualitative observations.
Such an assessment of the overlap between predictions would also help in designing a hybrid method that takes advantage of the strengths of different methods.
Accordingly, this contribution explores the potential of citizen science initiatives in forest monitoring from a high-level perspective through an assessment of topical overlaps in the published literature on "citizen science" and "forest monitoring".
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Justyna Jupowicz-Kozak
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