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Historically, a large percentage of these boys have undergone surgical repair with the belief that such early presentation carried a worse prognosis, making assessment of longitudinal outcomes difficult.
While the apical view is essential for the tissue Doppler imaging assessment of longitudinal strain and strain rate, the advent of more sophisticated speckle-tracking strain post-processing software has been able to overcome this limitation.
This study evaluates the performance of the elastix toolbox deformable image registration algorithm for VOI and voxel-wise assessment of longitudinal variations in FDG tumor uptake in NSCLC patients.
Eight studies of poor methodological quality [24, 29, 45, 46, 55, 60, 72, 73] were limited by insufficient participant numbers to satisfy rating classification as fair in addition to four of the mentioned studies investigating acute responsiveness [41, 75 77], therefore not enabling assessment of longitudinal responsiveness.
However, both heterogeneity in disease progression speed and individual variation in baseline cystatin C levels could mask significant trends in cystatin C change over the course of disease progression and, therefore, single-draw protein levels are unsuitable for a thorough assessment of longitudinal trends in cystatin C abundance.
Additional file 2: Quality assessment of longitudinal studies.
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Path analysis will be constructed to adjust these assessments of longitudinal changes using groups of covariates (disease and treatment variables; demographic variables; social support; and pre-existing mental health variables).
Patient function was measured pre-operatively, providing a baseline with which to compare post-operative function, but there was no independent assessment of possible longitudinal changes, assessed with a control group, nor was the assessment blinded.
Assessment of myocardial longitudinal function has proved to be a sensitive marker of deteriorating myocardial function in aortic stenosis, demonstrated by both color Doppler tissue imaging and recently by two-dimensional speckle-tracking echocardiography.
The data collection process for the assessment of the longitudinal construct validity of the DASH has been described previously [ 10].
Among the various parameters for the assessment of LV longitudinal myocardial function, GLS is thought to be the most reliable marker and to have good reproducibility [ 35].
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