Sentence examples for assessment of compound from inspiring English sources
The assessment of compound synthetic feasibility can be done either manually, or computationally.
The early assessment of compound toxicity is crucial in drug discovery to dismiss drug candidates displaying undesirable safety profiles.
Therefore, the combination of both methods permits the assessment of compound polypharmacology and provides quantitative bioactivity predictions.
The combination of both methods permits the assessment of compound polypharmacology and provides insight into the potency/affinity of small molecules.
Subsequently, activities of compounds on previously untested kinases could be predicted as a weighted average of prediction of the same compounds from neighboring models, allowing for assessment of compound promiscuity within the kinome [34].
This paper presents the development and an application of a multidisciplinary methodology for the preliminary design assessment of compound coaxial rotorcraft with a counter-rotating rotor system and a rear-mounted propeller.
In general, there is no scenario in which one should use a grid search approach (it is always preferable to use random search or a Bayesian method) or SVMlight heuristics (it is always better to use libSVM) in the tasks connected with the assessment of compounds bioactivity.
The new structural alerts may aid in the predictive inhalation toxicity assessment of compounds as well as in designing low-toxicity chemicals, and provide a rationale for the chemistry underlying the toxicological outcome that can also be used for scoping targeted experimental studies.
AMS is an attractive method to determine human pharmacokinetics, DNA binding, and other potential biomarkers of importance in risk assessment of compounds with potential toxicity.
The separation step allows the individual assessment of compounds in a mixture and links affinity and structure information via the retention time.
The approach used was an efficient way at summarising priority knowledge gaps as a starting point for health risk assessment of compounds, based on their relevance for the risk assessment outcome.
