Therefore, a better assessment marker of the fibrosis activity and comprehensive understanding of the underlying mechanisms of collagen over-production may provide new strategies for the anti-fibrotic treatment of SSc.
Autoimmune conditions like GBS can stimulate the production of a high level of inflammation resulting in an increase in the CRP production, so highly sensitive CRP assay may become a new risk assessment marker in the future for autoimmune disorders including GBS (Vaishnavi et al. 2014).
This study was designed according to the predictive marker trial design 'Indirect assessment: marker by treatment interaction design, test of interaction' (design 2) [ 25].
For large-scale ASE assessment, the markers must be reproducibly typeable and reasonably informative.
Assessment of markers associated with bone turnover in AS has contributed to elucidating key pathways linked to the disease.
Standard urine cytology (Papanicolaou staining test) for the assessment of markers indicative of bladder cancer was performed.
Early-morning fasting urine and serum samples were collected at baseline and at months 3, 6, and 12 for assessment of markers of bone and cartilage turnover.
35 We are also collecting laboratory clinical test results on preoperative assessment, tumour markers, and pathology reports for patients with thyroid cancer (figure 1).
