The subjects are not required to have exactly the same numbers of assessments, and even the assessments can be made at variable times.
In addition, the i.v. infusion paradigm also maintained steady-state plasma exenatide concentrations over a 6 h ECG assessment period, allowing selection of time points for QT assessment at which pharmacodynamic variables were stable.
For analyses for each of these 3 global assessment variables at each school, in 8 of the 9 comparisons, JHLES was more strongly correlated with the global assessment item than was DREEM.
Frequency distributions were determined for pediatrician skin assessment variables at baseline (before and after product application), weeks 3 and 6, and the change from baseline to weeks 3 and 6 for the arms, legs, and torso.
It is estimated that the error rate with common genotyping techniques is less than 10%, while it can be as high as 50% for environmental exposure assessment, at least for dichotomous exposure variables.
For the secondary outcome measures, namely psychological distress and functional limitations, the same analysis will be repeated, but with the secondary outcome measures at the second assessment as dependent variable, and the scores at baseline as covariate.
*Indicates assessment of a variable at the timepoint indicated.
For all other variables, the baseline was defined as the assessment at the screening visit.
In addition to the baseline assessment, the variables were also reassessed at two week intervals from the 2nd week to the 12th week.
†: Assessment at 42 days.
