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An experimental autoimmune encephalomyelitis (EAE) model of MS was utilized to assess time dependent gene and protein expression changes of CX3CL1 and CX3CR1.
Assessing time-dependent material property deterioration, often a concern for polymers and their composites, is essential to evaluating the viability of novel materials to serve as lower environmental impact replacements for conventional materials.
We had no possibility of assessing time-dependent changes in cytokine gene expressions.
This paper presents a new approach to assess time-dependent corrosion fatigue damage of welded joint considering the coupling effect between mechanical factor and corrosion factor.
Cunningham et al [38] assessed time-dependent changes in LBP serum concentrations in 121 trauma patients on hospital admission and at 24 h.
The primary analysis used Cox proportional hazards regression to assess time-dependent risk of post-index psychiatric hospitalization with a pre-specified threshold for statistical significance of p < 0.05.
A few previous fMRI studies on cross-modal learning have assessed time-dependent activation changes during AV learning (Gonzalo et al. 2000; Tanabe et al. 2005) or changes in functional connectivity between unimodal cortices (von Kriegstein and Giraud 2006).
The terminology to define outcomes in this study was slightly modified as compared with the original protocol because it is more precise and less subjective to assess time-dependent clinical complications in cirrhotic patients.
We assessed time-dependent changes in protein expression in S49 cells in response to increases in the level of cAMP to identify proteins that may be primary targets of cAMP/PKA (at an earlier, 6 h, time point) while proteins with altered expression after 24 h likely include secondary ones.
Overall, this study provides guidance to select proper statistical tool for the assessing the time dependent variation of diffusion coefficient.
Multivariate analysis will be carried out to assess time changes of dependent variables.
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