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An external statistical company assessed this analysis independently.
Due to the relatively small number of tumors assessed, this analysis would greatly benefit from expansion into a larger cohort that could highlight which genes and pathways are most important to sGBM gliomagenesis and progression.
In order to assess this, discriminant analysis [ 19] of the RT-PCR data was performed.
Thirdly, outcome measures and length of follow-up for outcome assessment were not assessed in this analysis.
Independent (Predictor) Variables: The following nutritional markers were assessed in this analysis: serum albumin, energy intake, protein catabolic rate, serum creatinine, midarm muscle circumference, calf circumference, and smoking status.
Clearly, this cannot be assessed in this analysis.
Furthermore, only the primary efficacy outcome was assessed in this analysis (ASAS20).
The reference definition has practical advantages compared to the other definitions assessed in this analysis.
All single technology appraisals across the four agencies were assessed in this analysis.
We took a social ecological approach to identify factors to be assessed for this analysis (Bronfenbrenner 1979).
Furthermore, due to the short study duration, end-stage renal disease events were not assessed in this analysis.
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