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We assessed the quality of the parameters estimated by ABC by assessing the determination coefficient R (the proportion of parameter variance explained by the summary statistics), by analyzing pseudo-observed datasets and by posterior predictive tests [ 27], as detailed in the Additional file 1: Section 1.5.
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Further studies of larger samples are warranted to assess the determination of CRP levels by polymorphisms in other genes.
The authors used data from the ArboNet system such as number of virus-positive birds, mosquitoes and humans and evaluated the models predictive ability by assessing the coefficient of determination (R) [ 15].
Plasma samples with positive W. bancrofti microfilarial count were tested by ICT and ELISA assays to assess the threshold determination regarding CFA plasma level.
However, its determination allows assessing the degree of anticoagulation and determining the pharmacodynamics of anti-Xa activity.
Moreover, circulating levels of miR-25 were correlated to the residual beta-cell function (assessed by C-peptide measurement) and with adequate glycemic control (assessed by the determination of glycated hemoglobin) three months from T1D onset [ 80].
Passive phase of relaxation and filling was assessed by the determination of end diastolic compliance during a preload reduction manoeuvre.
The distribution of the subpopulations of cells was assessed by the determination of the response of every cell in every experimental run.
The ability of network to model drug release has been assessed by the determination of correlation between predicted and experimentally obtained data.
The performances of these models were assessed through the determination coefficient (R2), F-ratio, standard error of estimate and root mean square error (RMSE).
Performance of the score was assessed by the determination of the discrimination (area under the ROC curve: AUC) and the calibration (Hosmer Lemeshow test).
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