Prior to unblinding, an independent Data Review Committee, which consisted of R. Wilson, A. Anzueto, M. Miravitlles and S. Sethi, assessed the data for all patients who were clinical failures or had indeterminate assessments in order to confirm the primary clinical outcome.
We then assessed the data for completeness, consistency and accuracy.
The D'Agostino and Pearson omnibus test was used to assess the data for normality.
PRIMUS [ 28] was used to assess the data for aggregation and to perform Guinier analysis.
We used computerized edits to assess the data for logic errors, out-of-range values, missing data, and multiple responses.
Histograms and plots were used to check for unexpected and outlying values and to assess the data for normality.
To detect possible genotyping error, for family data, we assessed the data for Mendelian consistencies by the program PEDCHECK [ 54], with no non-Mendelian inconsistencies detected.
We assessed the data for evidence of LBA which would manifest itself in the data by drawing species with a greater number of mutations in the gene of interest together erroneously on the phylogenetic tree.
We used both descriptive and analytic techniques to inspect and assess the data for the 705 girls for whom stored residual sera were available for hormone measurement of which 689 (98%) had sufficient sample for inhibin B analysis.
16 40 42 We assessed the data for multidirectional relationships between the domains; however, in contrast to previous studies, 16 children in this study did not describe emotional well-being having an effect on physical activity, school or socialising.
