Exact(23)
When assessing survival time, survival state, tail injury, and the body weight of mice, it was found that the NK-TUDCA complex (NK: 10 kIU/ml; TUDCA: 10 mg/ml; pH 5.0) had a lower toxicity when administered at an NK dosage of 130 kIU/kg in the acute toxicity test and 13 kIU/kg in the repeated low-dose challenge.
Given the paucity of prospective randomized controlled trials assessing comparative performances of different dialysis techniques, we compared on-line high-flux hemofiltration (HF) with ultrapure low-flux hemodialysis (HD), assessing survival and morbidity in patients with end-stage renal disease (ESRD).
The analysis generated a set of regression models that, when weighted and combined according to posterior probabilities implied by the statistical analysis, identify patterns in expression of a small subset of genes that are associated with survival and have value in assessing survival risks.
Apart from endpoints assessing survival time such as OS and PFS, endpoints regarding morbidity in terms of symptoms and complications of a disease as well as HRQoL also represent endpoints for PRB in pivotal studies, are recognized by regulatory agencies and must also be accepted in principle for EBA.
This method of assessing survival correlates well with other cell survival assays such as trypan blue exclusion and staining with calcein AM [14].
Each of these measures has its advantages and disadvantages, but, at least, in life-threatening diseases such as cancer, assessing survival seems to be the key determinant of true success rate.
Similar(37)
We assessed survival, below- and aboveground biomass, and physiology (chlorophyll a fluorescence).
The purpose of this study was to assess survival and morbidity when completion hysterectomy follows radiation for bulky cervical cancer.
This article assesses survival at life-threatening RBC hemoglobin concentration ([Hb]) in massively bleeding patients who do not receive red cells.
This multicenter phase III trial assessed survival of patients resuscitated with a hemoglobin-based oxygen carrier starting at the scene of injury.
Cox analysis was used to assess survival.
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