We assessed baseline differences between groups with Student's t-test, the Mann Whitney-U test, and chi-square tests.
Unpaired Student t-tests were used to assess baseline differences between groups for continuous variables and Chi-Square was used for categorical variables.
Fisher's exact test was used to assess baseline differences between the C-SLE groups in the drug regimen.
Methodological quality of experimental studies (randomised controlled trial, clinical trials, controlled before and after studies) was assessed for sample formation, baseline differences between groups, unit of allocation to groups, measures of outcome and follow-up (Appendix A1).
Baseline differences between groups were assessed using t-tests for continuous outcomes and chi-squared tests for categorical outcomes.
For outcome variables (VT, Crs, respiratory distress syndrome severity score (RDS), ECMO flow), baseline differences between groups were assessed using Student's t test.
Baseline differences between groups were assessed by Chi-square or Fisher's exact test and Student- t or Mann-Whitney U test, as appropriate.
There were no baseline differences between groups.
We controlled for baseline differences between groups in our analysis.
Assessing baseline adjusted between-group mean difference between NAC and placebo group from baseline up till week 20 in urine samples to explore biological correlation in DNA and RNA damage by oxidative stress.
Assessing baseline adjusted between-group mean difference between NAC and placebo group from baseline up till week 24 on MADRS, MES, YMRS, WHO-5, GAF-F, GAF-S, CGI-S and urinary markers.
