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The assumptions of parametric statistical tests were assessed via tests of normality and homogeneity of variance.
Differences in characteristics between groups were assessed via tests appropriate to the data.
For each nutrient, both within- and between-group designs were used to assess (via two-bottle preference testing) whether flavor nutrient learning had occurred after 2, 4, or 6 training trial pairs.
Children's IQ was assessed via individual testing at age 5 years.
The differences in protein expression between parent and isogenic mutant was assessed via hypothesis testing, specifically a comprehensive ANOVA scheme included in the computer program DAnTE [30].
Differences in protein expression between parent and iosgenic mutant was assessed via hypothesis testing, specifically a comprehensive ANOVA scheme included in the software program DAnTE.
Statistical significance was assessed via χ test of Fisher's exact test for categorial variables and Student's test or the Mann–Whitney U test for continuous variables.
Differences in subject characteristics between groups were assessed via t-test for continuous variables and Chi-squared test for categorical factors.
Group differences in demographic, clinical and metabolic variables were assessed via t test, analysis of variance (ANOVA) or χ tests where relevant.
Allelic heterogeneity among rivers was assessed via genic tests in GENEPOP v.4.0.6 (Rousset 2008) using default parameters for all tests.
Neurocognitive performance was assessed via computerised test battery after 50 min of breathing a gas mixture that reduced arterial oxygen saturation by 20% (p < 0.01).
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