Recent, significant advances in protein engineering have come through computational methods, such as SCHEMA, ProSAR, and ROSETTA.
A digital transformation of genomic sequences has facilitated the biological discovery of regulatory regions in the genome through computational methods.
This study has found four good candidates for Giardia snRNAs through computational methods, and confirmed by RT-PCR analysis that they are highly expressed.
As more and more genomes come online faster and faster, functional annotation is more and more being done through computational methods rather than by experiment.
Identifying anticancer drug response markers through computational methods is highly promising for cancer precision therapy [ 63].
Therefore, their identification through computational methods requires strategies based on local alignments.
There are several challenges that need to be addressed when approaching this problem through computational methods.
The BioCreative IV GO workshop (5) aims to automate gene function curation through computational methods.
Predicting expression level of genes through computational methods is appealing because it circumvents expensive and difficult experiment.
Through computational methods alone there are no means to conclusively determine whether a genomic region is functional.
Through the combined efforts of algorithm development and improved modeling accuracy, increasingly complex biological models become feasible to study through computational methods.
