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Secondly, we assessed the involvement of defined endocytic pathways in the internalization of the polyplexes in ARPE-19 cells by using a combination of endocytic inhibitors, RNAi depletion of endocytic proteins and live cell fluorescence colocalization microscopy.
To gain further insight into the mechanism of ROS-induced autophagy and apoptosis, we next assessed the involvement of the two critical MAPK family members, JNK and ERK.
We have previously assessed the involvement of NF-κB family members in HIV replication that occurs during the peak of virus-induced death by demonstrating that a super repressor form of IKBα blocks HIV replication, thereby implicating NF-κB family members as the dominant transcriptional mechanism that drives such HIV replication [20].
We also assessed the involvement of calcium influx during the repression of Muc2 induced by rVvpE.
We also assessed the involvement of calcium influx during the apoptosis induced by rVvhA.
This study assessed the involvement of the public and private health sectors in this increase.
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Furthermore, we assessed the involvements of CASP3 activity and mitochondria-mediated pathway in response to CASP8 in our system.
A large study was conducted to assess the involvement of eyes in patients with candidemia.
The present study was designed to assess the involvement of AVP as mothers acquire reproductive experience.
We were interested to assess the involvement of Notch1 signaling on cell proliferation of myeloid progenitor cells.
Further, this approach was also used to assess the involvement of MAPK cascade in UV induced expression of genes in PA biosynthesis.
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