Sentence examples for assessed the functional effects from inspiring English sources
Having established that Myc inhibition impairs autophagosome formation, we next assessed the functional effects of this on autophagy substrate accumulation.
We assessed the functional effect of the novel variant p.Asp1113Asn in the binding to dopamine receptor type 2 (D2DR), one of the few known interactors of CADPS2 (Binda et al, 2005), compared to wild-type CADPS2.
Finally, it was important to assess the functional effects of a variety of the observed, native PTPRS mutations.
We assess the functional effects of somatic mutations on SC proliferation and differentiation and predict the global consequence on muscle aging and sarcopenia.
A complete understanding of human cancer variants requires new methods to systematically and efficiently assess the functional effects of genomic mutations at a large scale.
In one arm of the screen we used electrophysiology to assess the functional effects of the library compounds on full-length EAG1 channels.
In this study, we used recombinant Wnt3a to assess the functional effects of canonical Wnt signaling in epithelial cells and fibroblasts.
To assess the functional effects of aptamers, U87MG (300 000 cells per 3.5-cm plate) were serum starved for 2 hs and then treated with the RNA aptamers or the starting RNA G0 pool prior subjected to a short denaturation-renaturation step.
Systematic studies using both in vitro and in vivo assays to assess the functional effects of mutations that alter the sequence, but preserve (or destroy) the conserved RNA structural motif, will be required to fully evaluate its potential biological significance.
In order to assess the functional effects of different action potential (AP) kinetics in VSD imaging in cultured cells, we have simulated an 'mmature'and a 'mature' Na+-current (INa) in cultured cells using the dynamic clamp technique.
To assess the functional effects of this cleavage, we generated truncated forms of REDD1 corresponding to the cleavage products.
