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The compounds developed were assessed on their affinity for serotoninergic receptors 5-HT1A, 5-HT7, 5-HT7 and α1-ARs in radioligand binding assays.
The compounds were assessed on their affinity for 5-HT1A and α1-adrenoceptors and evaluated in functional bioassays for antagonistic properties.
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They are assessed on their performances only".
These derivatives were assessed for their affinity ([3H]CPX), potency, and intrinsic activity (cAMP accumulation) at the A1 adenosine receptor in DDT1 MF-2 cells.
The first strategy utilizes identification of proteins based on their affinity to telomeric DNA.
IL-2Rs are classified into three subtypes based on their affinity for IL-2.
The influence of binding proteins on the quantification of IL-13 depends on their concentration, on their affinity for IL-13 at low pH, and on the affinity of assay capture antibody under the same conditions.
For quantitative characterizations of the quasi-specific sites, we first assessed their relative affinities with respect to the target site.
Based on these, energetically favorable and unfavorable contributions to the binding affinity can be assessed on an atomic level.
Equal protein content during affinity precipitation was assessed on acetone-precipitated supernatants.
A competitive bioassay based on immobilised rhuPAR was developed to assess their binding affinities.
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