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All parameters assessed indicated that high quality data were obtained (Fig. 1).
Three reports (0.7% of 428 total investigations or 0.5% of 567 total cancer types assessed) indicated that at least some evidence was found of an association between the cancer(s) of concern and hypothesized exposures, although the level of certainty of these findings differed.
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The possibility of using overlap analysis for deriving the regularisation parameters was assessed, indicating that for the moment this method is sub-optimal.
Finally, drug-likeness and ligand efficiency were assessed indicating that both 2 and 10a are promising hits and/or leads as anti-leishmanial chemotherapeutic agents.
The xylanolytic activity produced by L. ramosa H71D in the presence of Beechwood xylan or CMC was assessed, indicating that xylanase activity was greater when the fungus was cultured on CMC compared to than that observed for Beechwood xylan as carbon source; thus, indicating that CMC is more effective for the production of xylanase activity by L. ramosa H71D, under the culture conditions tested.
There were no significant differences among the groups assessed, indicating that splenomegaly was not a prominent feature in NASH rats.
As expected, malignancy is ruled out for the majority of women assessed, indicating that the result of their mammography was falsely positive.
However, we identified pattern I p62 aggregates in 8 of 11 (73%) further cases of IBM − RV that were assessed indicating that they may have a greater sensitivity and that p62 IHC warrants further investigation and validation in a larger, independent series.
32 Our sample size calculation, which took account of the likely degree of clustering from our pilot and feasibility studies and the number of outcomes that we planned to assess, indicated that we needed a total of 1500 participants from 60 schools to be randomised and 1275 included in the primary analyses.
Although the duration and intensity of PA were not assessed, results indicated that adolescents do not get enough practice to meet the recommended levels of 60 min of moderate to vigorous PA each day.
The morphology of H&E-stained sections from all treated joints (5 × 106 pfu/vector/joint) was assessed, and indicated that the contralateral joints treated with the control vector showed no evidence of bone damage (Fig. 1a).
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