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Repeatability and reproducibility were assessed by coefficient of variation (CoV) and intraclass correlation coefficient (ICC), based on 2-way random-effects analysis of variance.
The internal consistencies were 0.84, 0.88 and 0.84 at pre-mentoring, 6 months and 1 years respectively, as assessed by coefficient alpha.
The reliability of the DLQI, as assessed by coefficient alpha, was 0.89 at baseline and 0.92 at Week 12, indicating that this is a highly reliable measure, and in line with previous findings [ 27, 28].
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With respect to accuracy assessed by coefficients of variation (CV) between five parallel assays both methods performed equally well, and the CV values between parallel assays were indistinguishable between genomic DNA and reverse transcribed cDNA samples.
Repeatability and reproducibility were assessed by the coefficient of variation (CoV) and intraclass correlation coefficient (ICC).
Reproducibility of EVLW measurements was assessed by the coefficient of variation (CV) and intraclass correlation coefficient (ICC).
Correlations were assessed by Pearson coefficient.
Validation was assessed by the coefficient of determination and RMSE for each phenological development stage.
The goodness of the above relationships was assessed by the coefficient of determination (R 2 ) achieved from the regression analysis.
The goodness of fit with models was assessed by the coefficient of determination (R2) and Akaike information criterion (AIC) (Zhou et al. 2016).
For question 8, the dichotomous (yes/no) response options were scored yes = 1 and no = 0, and reliability was assessed by Kappa coefficient.
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