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Second, BMI as with physical activity was based on self-report and assessed at one point in time, which may have biased our results towards the null.
35 The data on prognostic factors was self-reported and assessed at one point only.
Study limitations are that data on prognostic factors were self-reported and assessed at one point only.
Quantity and quality of sleep were assessed at one point in all studies.
Finally, this study suggests that the quality of prescribing performance should not be assessed at one point in time, since there may be temporary, valid reasons for not yet prescribing specific medication.
One limitation is that although the retro-pre model may reveal valuable information, it is not a substitute tool for an objective measure or a gold standard, but can be used where a large number of skills are to be assessed at one point in time.
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Participants included 28 individuals with ASD and 33 TD controls matched on age and IQ and assessed at one time point.
Changes in decision making were also assessed at one fixed point during the clinical assessment, preventing us from examining the impact of iterative use of the DDSS with evolving and sometimes rapidly changing clinical information.
Our assessment: Only one primary outcome is reported in the published protocol (http://www.thelancet.com/protocol-reviews/05PRT-1) and this outcome is only assessed at one time point.
One of the possible explanations could be that the periodontal destruction is a cumulative condition, while use of medication was assessed at one time point.
Patients in the cross-sectional study were assessed at one time point only, whereas patients in the longitudinal study were assessed at pre-treatment baseline, and at 2 weeks and 3 months after treatment with anti-TNF-α.
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