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Maternal education was assessed as completed years of schooling, and dichotomized to primary education, i.e. <6 years, and more than primary education, ≥6 years of schooling.
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Clinical response data for patients who received chemotherapy was assessed as follows – complete remission was defined as the disappearance of all parameters of the disease; partial remission was defined as a 50% reduction in the size of tumour mass as defined radiologically and progressive disease was defined as a 25% increase of any tumour mass or the development of a new lesion.
No patient was assessed as complete response or partial response.
If the outcome was assessed as complete recovery at the 4- or 10-week return visit, the prednisolone therapy protocol described above was followed.
Women with a negative LSUP-test, assessed as complete abortion at the time of follow-up, will be censored out of the study.
Objective tumour response was assessed as complete response (CR), partial response (PR), stable disease (SD) or disease progression every 6 weeks according to the International Union Against Cancer/World Health Organisation criteria (Green and Weiss, 1992).
Tumour response was assessed as complete response (CR), partial response (PR), stable disease ≧12 weeks (SD), or PD in accordance with the standard Response Evaluation Criteria In Solid Tumours (RECIST).
Nanoparticle exposure was assessed as follows.
Statistical significance was assessed as indicated.
Genome completeness was assessed as follows: Complete genomes have a complete set of single copy genes (Raes et al., 2007), and the linkage between all scaffolds is established; Near complete genomes have a complete set of single copy genes, and the linkage between almost all scaffolds is established; Partial genomes lack a complete set of single copy genes, and/or scaffold linkage is lacking.
For all fissures visually assessed as being complete the automatic method resulted in significantly higher completeness scores (mean 92.78%) than for those assessed as being partial or absent (mean 77.16%; all p values <0.001).
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CEO of Professional Science Editing for Scientists @ prosciediting.com