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We would encourage other groups that may be interested in using this instrument to assess instrument reliability in their setting prior to use.
To assess instrument feasibility, the percentage of missing values was calculated.
Cyto-Cal calibration beads (Thermo Fisher Scientific, Waltham, MA, USA) were used to assess instrument stability.
Cyto-Cal calibration beads (Thermo Scientific, Runcorn, UK) were used to assess instrument stability.
To assess instrument validity, we evaluated the association between survey responses and known predictors of sexual and urinary function.
Cronbach's alpha, exploratory factor analysis, analysis of variance, and tests of association were used to assess instrument reliability and validity.
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As a first step towards conceptualising alternatives previous evaluations and stakeholder interviews are used to assess instruments.
2SLS has the added benefit of providing an easy method for assessing instrument validity.
Receiver Operating Characteristic (ROC) analysis assessed instrument responsiveness to change.
This study used a subsample of PRO instruments identified in a wider study assessing instrument quality.
More studies assessing instrument acceptability and preferences of clinicians and people with MS are also needed.
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