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These subsystems include assertions of function for well over 500,000 protein-encoding genes in over 500 bacterial and archaeal genomes (relating to over 6200 functional roles).
This captures a kernel of truth (that, ultimately, new assertions of function are based on wet lab characterizations), but, perhaps, elevates the role of bioinformatics beyond what is reasonable to expect.
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However, our data, corroborated by recent observations of Colin et al. (2014), support the assertion that WDR73 loss-of-function is sufficient to cause NCS on the Galloway-Mowat spectrum.
The assertion that heterozygous loss of function mutations in POGZ cause diverse NDDs is further supported by the presence of two CNVs encompassing POGZ coding regions in the DECIPHER database [ 29].
It is commonly held that one central role of bioinformatics is to project a relatively small set of assertions of gene and protein function from the literature (i.e., from wet lab characterizations) to genes from other genomes.
(Initializers for functions' local variables are evaluated before assertions are checked, so be careful not to assume that an argument is valid in an initializer). You can also sprinkle assertions throughout the body of functions in places where you suspect things are likely to go wrong.
According to the assertions of the theorem, the inverse of the function, given by (2.61). is differentiable and fulfills the basic difference equation (2.62).
Let the Schrödinger equation (1.1) be given, fulfilling the assertions of Definition 1.1 where In addition, the function will have the property (1.3).
First, de novo protein design has complicated the assertion that biological function is equivalent to biological structure — demonstrating the capacity to abstract active sites from natural contexts and paste them into non-native topologies without loss of function.
Note that by construction, the function now fulfills all the assertions of Theorem 3.2.
Reject premature assertions of cause and effect between brain structures and functions.
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