Sentence examples for assembly specificity from inspiring English sources

Structural analysis indicates that a limited set of interactions encode assembly specificity determinants and uncovers a previously unnoticed segregation of TRPM assembly domains into two families that correspond with the phylogenetic divisions seen for the complete subunits.

With the caveats discussed below, the overall pattern we observed is consistent with the idea that evolution selects for diversification of assembly specificity within families of paralogous proteins.

The linear ubiquitin chain assembly specificity of HOIP is preserved in HOIP RING1 mutants and RING1/IBR mutations do not affect the E2-independent activity, indicating that these domains are not used in the actual linkage formation between two ubiquitins.

Despite recent advances in PP2A structural biology, many questions remain about the mechanisms underlying PP2A holoenzyme assembly, substrate specificity, and regulation.

Simple design, fast and low-cost assembly, high specificity combined with low cytotoxicity and a practically unlimited target site selection make TALE DBDs an excellent choice for DNA targeting.

As a further link, the assembly and specificity of the SNARE complexes are described to be regulated by Rab GTPases (reviewed in [ 56]) of which several are potential downstream targets of the trans-Golgi-associated cascade ARFRP1-ARL1-Golgin-Rab and could therefore influence LD fusion [ 45].

How the specificity of assembly evolves is a fundamental question of biology.

Additional sequencing would be expected to increase the transcriptome space coverage which would ultimately improve the specificity of assembly.

Only one compound (vincristine sulfate, an inhibitor of microtubule assembly [24]) demonstrated greater specificity for human fibroblasts compared to T. brucei.

How this remarkable specificity of assembly is achieved in the crowded environment of quiescent cells remains to be determined, but some of the principles presented here may apply more generally.

The deviation of five amplicons from the expected size may have been due to the presence of introns [ 63, 64], large insertions or repeat number variations, a lack of specificity, or assembly errors.