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The results show that for any higher order assembly of the network, optimal internal radius ratio is always 21/2 for wetted surface constraint, and 23/7 for total duct volume constraint.
Based on these studies, it is possible that knock down of proteins that reside at focal adhesions probably may lead to incomplete or improper assembly of the network of proteins found at the focal adhesions.
This modular architecture makes assembly of the network considerably simpler than the result appears in Fig. 2. To facilitate clarification of subsequent diagrams, one of the excitatory connections is drawn in green in Fig. 4F, G. Non-hexagonal n-RANCs for the outputs labeled 2n−1−1 and 2n−1 are also modular, as described previously in the recursive process for constructing them.
Where possible, experimentally high-confidence causal relationships were used to construct the regulatory networks following the same approach adopted during the assembly of the network models used in RCR analysis.
Vasculogenesis is a de novo assembly of the network, whereas angiogenesis is the coordinated growth of endothelial cells (ECs) from pre-existing vasculature (Risau, 1997; Risau and Flamme, 1995).
Combining two well-developed algebraic, discrete and logical methods (Boolean network construction and FCA) it was possible to include human expert knowledge in all different phases (assembly of the network, adjustment to the data, and choice of relevant temporal rules), with the exception of the challenging data discretisation step.
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The assembly of the networks exhibited in Fig. 2 and Fig. 3 were initially loaded with only the differentially regulated genes from the respective datasets.
Constructal optimizations of elemental, first order and the higher order assemblies of the network are performed by taking minimum overall pressure drop and maximum overall temperature difference as optimization objectives.
To address whether Spire1- and Spire2-dependent F-actin nucleation is required for assembly of the actin network, we analyzed the network in the center of the oocyte by high-resolution confocal microscopy.
During this interval, the coat transitions to a more stereotypical behavior and prepares for assembly of the actin network.
De-methyl-esterified HG (henceforth HGA) may affect assembly of the cellulose network, influencing the deposition and alignment of microfibrils in the wall [ 14].
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