Sentence examples for assembly of regions from inspiring English sources

It automatically combines mapping against a closely related reference genome and de novo assembly of regions that cannot be mapped to the reference.

In contrast, the assembly of regions far from these sites was made possible by sub-families with additional recognition sites for one of these enzymes.

Allowing for mismatches where genes had low expression levels resulted in a decrease of fragmentation in assemblies with high k-mer sizes indicating that the additional reads were crucial for the assembly of regions with low coverage.

The main advantage of a clone-based approach compared to WGS is that it facilitates the accurate assembly of regions harboring multigene families and transposable elements (TEs) that are repeated at the genome level but not at the clone level [ 5].

Applications of some of the new long-range haplotyping techniques, particularly those capable of de novo assembly of regions of personal genomes within the MHC that are not in the reference genome, are likely to allow better utility of MHC typing for research, prognostics, diagnostics, and tissue transplantation [ 93].

Our assembly methodology is based on first ordering the clones and subsequently performing read assembly in three stages: (1) local assemblies of regions significantly smaller than a clone size, (2) clone-sized assemblies of the results of stage 1, and (3) chromosome-sized assemblies.

In de novo sequencing of a genome, repeats are usually assembled after the assembly of unique regions, and assemblers use multiple paired-ends to link a repetitive contig to a unique one.

Repeated sequences longer than 600 bases, such as IS-elements and the rrl and rrn genes, were identified and curated manually to ensure that at least two templates spanned these regions, thus confirming the assembly of these regions.

Due to assembler's insufficient accuracy in assembly of repeat regions, manual curations of the IRs were carried out using the BLAST2Seq program by comparison of the scaffolded regions with the N. officinale plastome.

This implies that the assembly of new regions of a DNA molecule must occur on a template of DNA already present in the cell.

The nonwoven fabric is treated as an assembly of two regions having distinct mechanical properties: fibre matrix and bond points.