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These methods use an assembly of features from protein pairs to learn the difference between interacting and non-interacting pairs, and then score the new interaction predictions.
The use of multi-parameter analysis, where many separate features are combined to define a specific cellular phenotype using an assembly of features (often called a 'feature vector') helps identify unique phenotypes and cluster genes with respect to cellular processes they are involved in 23, 24.
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We tested the performance of classifiers constructed by the assembly of different features iteratively.
This architecture is illustrated in Figure 2. The Ensembl datasources contain not only the actual DNA sequences of genome assemblies but also annotations of features on the assembly derived from Ensembl's own pipeline analyses and external sources, together with derived relationships between these features.
Because of this assembly of nearly ideal features, we explored the potential use of the IL-12 p40 as reporter gene to measure the activity of cis-genetic elements, and in high-throughput screenings of engineered mammalian cells.
It is based on the use of assembly features, i.e. pre-defined geometry elements that contain additional technological information.
Trimmed and cleaned sequences were assembled using the cDNA assembly feature of Newbler software v.2.3.
Trimmed and cleaned sequences were assembled using the cDNA assembly feature of Roche Newbler software v. 2.3 (Roche/454 Life Sciences).
By screwing the parts together without any adhesive material, MWNT electron source is developed from totally mechanical assembly with features of low outgassing rates, good emission stability, and the feasibility to replace the MWNT cathode.
The origin of the reflectin gene and assembly features of reflectin protein are of considerable biological interest.
A range of k-mer values were tested, and a final assembly was accepted on the basis of features such as total number of assembled contigs, N50 value and cumulative contig length.
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