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Since L11 is required for ribosome assembly, knocking down this protein should result in a ribosomal stress.
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To find the source of forced vibration of the armature assembly, a knocking method is proposed to measure the natural frequency of armature assembly.
The role of filamin A protein in RSV was studied using fusion protein cytoplasmic tail (FCT), which is critical for virus filamentous assembly by knocking down the protein gene expression using lentivirus-expressing shRNA against filamin A and inhibiting the expression of filamin A. The data showed that filamin A was not necessarily needed in the assembly of RSV [ 79].
To explore further the roles of adherens junctions and desmosomes in micro-epidermis assembly we knocked down the expression of P-cadherin (CDH3) and the major plaque component, desmoplakin (DSP, Fig. 3f).
A 9-year-old girl fell from her school's morning assembly platform and knocked her head against the ground.
This idea is further supported by a number of experimental observations: first, knocking down spindle assembly checkpoint genes, which results in high rates chromosome mis-segregation and high levels of aneuploidy, invariably causes embryonic lethality in mouse models (Foijer et al., 2008).
Knocking out components essential for their assembly prolongs a juvenile state of plasticity into adulthood (Carulli et al. 2010).
IFT22 also undergoes IFT in the flagellum of the protist Trypanosoma brucei but surprisingly knocking down the protein resulted in severe flagellar assembly defects, typical of inhibition of retrograde transport (Adhiambo et al., 2009).
Damaged racks could mean knocked-over assemblies, or assemblies leaning on other assemblies even a routine method of extraction runs the risk of knocking them around and playing havoc with the inner fuel rods.
Being awarded the chess cup at school, and then knocking it over on the school hall floor causing the most almightly clang in the middle of assembly.
Faced with an import duty of 91% on small cars assembled from "semi-knock-down" and 31% even for assembly from "complete knock-down", Hyundai, in common with its foreign rivals, decided to move straight to full manufacturing in India.
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