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While mated reads are expected to provide assembly benefits similar to longer reads, the connection to assembly quality is less clear and so we have not utilized this assumption as we have for read length.
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The Tcas5.0 assembly benefitted from the use of LongDistance Illumina Jump libraries to anchor additional scaffolds and fill gaps.
Some of these assemblies benefited from comparison to closely related species to improve the assembly.
Advances in nanoparticle synthesis and assembly have benefited this research are.
We demonstrated that de novo assembly could benefit a lot from these Sanger-like reads.
More experiments should be conducted in order to prove that assembly can benefit from the clustering preprocessing.
Projects that require more RAM than the fat nodes (72 GiB), such as de novo sequencing projects of large genomes and transcriptome assembly projects, benefit from the SMP.
Our understanding of the mechanism of β-barrel assembly is benefiting from comparative approaches, with findings on the assembly pathway in organelles informing studies on the pathway in bacteria, and vice versa.
Transcriptome assembly may benefit from the existence of multiple sample RNA-Seq data, but may also be confused by inherent RNA-Seq errors, which in turn affects downstream differential analysis.
As a consequence, despite the good overall quality of the chicken draft assembly, which benefited from the relatively small content of repeat sequences, a large fraction corresponding to 10 of the smallest microchromosomes was missing in the first version of the published sequence assembly (February 2004) [ 6].
Another approach to resolving repeats is through mixing long and short reads, to improve assemblies by benefiting from the respective advantages of the different technologies.
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CEO of Professional Science Editing for Scientists @ prosciediting.com